Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type	Study_count
Total_Studies	3610
interventional	2877
Observational	647
Registry	86

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type	Study_Count
Drug	1258
Drug\|placebo	427
Behavioral	313
Other	249
Device	169
Procedure	81
Dietary Supplement	66
Dietary Supplement\|placebo	48
Drug\|Other	33
Drug\|Procedure	27
Behavioral\|Other	25
Device\|Other	23
Device\|Drug	16
Diagnostic Test	16
Behavioral\|Drug	15
Behavioral\|Device	11
Device\|Procedure	10
Other\|placebo	8
Other\|Procedure	8
Drug\|Other\|placebo	6
Biological	5
Dietary Supplement\|Drug\|placebo	5
placebo	5
Radiation	5
Combination Product	4
Device\|Drug\|placebo	4
Device\|Drug\|Procedure	4
Biological\|placebo	3
Device\|Diagnostic Test	3
Device\|placebo	3
Dietary Supplement\|Other	3
Behavioral\|Procedure	2
Combination Product\|placebo	2
Dietary Supplement\|Drug	2
Behavioral\|Device\|Other	1
Behavioral\|Dietary Supplement	1
Behavioral\|Dietary Supplement\|Other	1
Behavioral\|Dietary Supplement\|placebo	1
Behavioral\|Drug\|placebo	1
Biological\|Diagnostic Test\|Drug\|placebo	1
Biological\|Diagnostic Test\|Other	1
Biological\|Drug	1
Biological\|Drug\|placebo	1
Biological\|Other	1
Dietary Supplement\|Drug\|Other	1
Dietary Supplement\|Drug\|Other\|placebo	1
Dietary Supplement\|Procedure	1
Drug\|Other\|placebo\|Procedure	1
Drug\|placebo\|Procedure	1
Drug\|Radiation	1
Genetic	1
Other\|Procedure\|Radiation	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	955
NA	311
Korea, Republic of	140
China	126
Japan	102
Brazil	82
Canada	79
Germany	74
United Kingdom	63
France	62
Spain	45
Switzerland	45
Denmark	32
India	23
Netherlands	21
Germany\|Switzerland	20
Austria	19
United States\|Germany	19
Taiwan	18
Egypt	17
Sweden	17
Turkey	16
Italy	15
Belgium	13
Norway	13
Mexico	12
United States\|Canada	12
Finland	11
Russian Federation	11
United States\|Puerto Rico	11
Greece	10
Australia	8
Israel	8
Cameroon	7
Singapore	7
Thailand	7
Ireland	6
Poland	6
South Africa	6
Pakistan	5
Peru	5
Portugal	5
Hong Kong	4
United States\|United Kingdom	4
Vietnam	4
Colombia	3
Ghana	3
Indonesia	3
Iran, Islamic Republic of	3
Malaysia	3
Nepal	3
Nigeria	3
Panama	3
Philippines	3
United States\|Germany\|Spain	3
Argentina	2
Australia\|New Zealand	2
Austria\|Germany	2
Bangladesh	2
Belgium\|Canada\|France\|Italy\|Netherlands\|Spain	2
Chile	2
China\|Japan\|Korea, Republic of\|Taiwan\|Thailand	2
Czech Republic	2
Czechia	2
Denmark\|Finland\|France\|Germany\|Hong Kong\|Ireland\|Italy\|Korea, Republic of\|Malaysia\|Netherlands\|Norway\|South Africa\|Spain\|Sweden\|Switzerland\|Taiwan	2
Denmark\|Finland\|Norway\|Sweden	2
Germany\|Netherlands	2
Germany\|Netherlands\|United Kingdom	2
Germany\|United Kingdom	2
Hungary	2
Jordan	2
Kenya	2
Lebanon	2
Moldova, Republic of	2
Romania	2
Saudi Arabia	2
Slovenia	2
United States\|Argentina\|Australia\|Austria\|Brazil\|Canada\|Chile\|China\|Denmark\|France\|Germany\|Greece\|India\|Israel\|Italy\|Korea, Republic of\|Mexico\|Netherlands\|Poland\|Singapore\|Sweden\|Taiwan\|United Kingdom	2
United States\|Argentina\|Mexico	2
United States\|Australia\|Austria\|Belgium\|Canada\|Czech Republic\|France\|Germany\|Italy\|Netherlands\|Poland\|Spain\|United Kingdom	2
United States\|Australia\|Austria\|Belgium\|Canada\|France\|Germany\|Italy\|Netherlands\|Spain\|United Kingdom	2
United States\|Australia\|Canada	2
United States\|Austria\|Germany	2
United States\|Belgium\|Hungary\|Slovakia	2
United States\|Belgium\|Ireland	2
United States\|Canada\|Puerto Rico	2
United States\|Chile\|Mexico	2
United States\|Dominican Republic	2
United States\|France\|Germany\|Italy\|Netherlands\|Switzerland\|United Kingdom	2
United States\|Iceland	2
United States\|Israel	2
United States\|Russian Federation	2
NA	1
Algeria	1
Algeria\|Argentina\|Brazil\|Colombia\|Ecuador\|Egypt\|Guatemala\|Lebanon\|Mexico\|Morocco\|Panama\|Peru\|Saudi Arabia\|Tunisia\|United Arab Emirates\|Venezuela	1
Argentina\|Australia\|Brazil\|Chile\|Guatemala\|Hong Kong\|India\|Indonesia\|Israel\|Jordan\|Korea, Republic of\|Kuwait\|Lebanon\|Malaysia\|Mexico\|Morocco\|Pakistan\|Peru\|Philippines\|Saudi Arabia\|Singapore\|South Africa\|Taiwan\|Thailand\|Tunisia\|Turkey\|United Arab Emirates\|	1
Argentina\|Brazil\|Chile\|Mexico	1
Argentina\|Chile\|Ecuador\|Finland\|France\|Germany\|Italy\|Norway\|Spain\|Sweden\|Switzerland\|Turkey	1
Argentina\|Germany\|Norway\|Poland\|Slovakia\|Sweden\|Turkey	1
Argentina\|United States\|Brazil\|Mexico\|Peru\|Puerto Rico	1
Armenia	1
Armenia\|Croatia\|Hungary\|Poland\|Russian Federation\|Serbia\|Slovenia	1
Australia\|Austria\|Belgium\|France\|Germany\|Netherlands\|New Zealand\|Switzerland	1
Australia\|Austria\|Bulgaria\|Czech Republic\|Ireland\|Italy\|New Zealand\|Russian Federation\|Slovakia\|Spain\|Switzerland\|Turkey\|Ukraine\|United Kingdom	1
Australia\|Austria\|Bulgaria\|Czech Republic\|Ireland\|Italy\|New Zealand\|Russian Federation\|Slovakia\|Spain\|Ukraine\|United Kingdom	1
Australia\|Belgium\|Czech Republic\|Denmark\|Italy	1
Australia\|Belgium\|Denmark\|France\|Germany\|Greece\|Ireland\|Italy\|Netherlands\|Spain\|Sweden\|United Kingdom	1
Australia\|Bulgaria\|Denmark\|Estonia\|Germany\|Hungary\|Israel\|Latvia\|Lithuania\|Slovakia\|United Kingdom	1
Australia\|Canada\|Czech Republic	1
Australia\|Czechia\|France\|Greece\|Pakistan\|Portugal\|Thailand\|United Kingdom	1
Australia\|Greece	1
Australia\|Poland	1
Austria\|Belgium\|Czechia\|France\|Germany\|Hungary\|Italy\|Latvia\|Poland\|Spain\|United Kingdom	1
Austria\|Belgium\|Czechia\|Hungary\|Latvia\|Lithuania\|Poland	1
Austria\|Belgium\|Finland\|Greece\|Hungary\|Ireland\|Italy\|Portugal\|Slovenia\|Spain\|Switzerland\|	1
Austria\|Belgium\|France\|Germany\|Hungary\|Italy\|Poland\|United Kingdom	1
Austria\|Belgium\|Italy\|Portugal\|Switzerland\|United Kingdom	1
Austria\|Czechia\|Germany\|Poland	1
Austria\|France\|Germany\|Netherlands\|South Africa\|Spain\|Switzerland\|United Kingdom	1
Austria\|Germany\|Italy\|Netherlands\|Portugal\|Spain\|Switzerland\|United Kingdom	1
Bangladesh\|Pakistan\|Sri Lanka	1
Belgium\|Brazil\|France\|Germany\|Guatemala\|Hungary\|Italy\|Lithuania\|Poland	1
Belgium\|Canada\|Czechia\|Egypt\|Germany\|Greece\|Hungary\|Israel\|Italy\|Netherlands\|South Africa\|Spain\|Turkey	1
Belgium\|Canada\|Denmark\|Finland\|France\|Korea, Republic of\|Netherlands\|Norway\|Philippines\|South Africa\|Sweden\|Taiwan	1
Belgium\|China\|Czechia\|France\|Germany\|Hungary\|Korea, Republic of\|Lithuania\|Mexico\|Poland\|Russian Federation\|Switzerland\|Thailand\|Turkey\|Ukraine\|United Kingdom	1
Belgium\|China\|Czechia\|France\|Germany\|Hungary\|Lithuania\|Mexico\|Poland\|Russian Federation\|Switzerland\|Thailand\|Turkey\|Ukraine\|United Kingdom	1
Belgium\|Colombia\|Finland\|Germany\|Israel\|Italy\|Mexico\|Netherlands\|Norway\|Peru\|South Africa\|Spain\|Sweden	1
Belgium\|Czechia\|Germany\|Poland	1
Belgium\|Denmark\|Finland\|France\|Germany\|Ireland\|Italy\|Netherlands\|South Africa\|Spain	1
Belgium\|France\|Germany\|Italy\|Poland\|Ukraine	1
Belgium\|France\|Germany\|United Kingdom	1
Belgium\|France\|Italy\|Netherlands\|Poland\|Portugal\|Spain	1
Belgium\|Germany\|Greece\|Ireland\|Netherlands\|Poland\|United Kingdom	1
Belgium\|Germany\|Italy\|Luxembourg\|Netherlands\|New Zealand	1
Belgium\|Israel\|United Kingdom	1
Belgium\|Latvia\|Malta\|Romania\|Russian Federation\|Slovakia	1
Belgium\|Lithuania\|Poland	1
Belgium\|Netherlands\|United Kingdom	1
Bolivia	1
Brazil\|Canada\|Ecuador\|Germany\|Hungary\|Korea, Republic of\|Malaysia\|Mexico\|Panama\|Philippines\|Singapore\|Slovakia\|Spain\|Turkey\|United Kingdom\|Venezuela	1
Brazil\|Chile\|Colombia\|Egypt\|Lebanon\|Mexico\|Morocco\|Tunisia\|Venezuela	1
Brazil\|Colombia\|Guatemala\|Mexico\|Morocco\|Tunisia\|United Arab Emirates\|Venezuela	1
Brazil\|India\|Philippines	1
Bulgaria\|Czechia\|France\|Germany\|Poland\|Spain\|Ukraine	1
Bulgaria\|Estonia\|Finland\|Germany\|Netherlands\|Poland\|Russian Federation\|Serbia\|Slovakia\|Sweden	1
Bulgaria\|Israel	1
Canada\|Costa Rica\|France\|Germany\|Greece\|Guatemala\|South Africa\|Switzerland\|United Kingdom\|Venezuela	1
Canada\|Croatia	1
Canada\|Denmark\|France\|Germany\|Italy\|Norway\|Spain\|Sweden\|United Kingdom	1
Canada\|Germany\|Netherlands	1
Canada\|Germany\|Netherlands\|United States	1
Canada\|United Kingdom	1
Canada\|United Kingdom\|	1
Canada\|United States\|Argentina\|Australia\|Austria\|Belarus\|Belgium\|Chile\|China\|Colombia\|Czechia\|Denmark\|France\|Germany\|Greece\|Hungary\|India\|Ireland\|Israel\|Korea, Republic of\|Malaysia\|Mexico\|Netherlands\|Peru\|Poland\|Romania\|Russian Federation\|Serbia\|Singapore\|Slovakia\|Spain\|Sweden\|Switzerland\|Taiwan\|Thailand\|Turkey\|Ukraine\|United Kingdom	1
Chile\|China\|Indonesia\|Korea, Republic of\|Mexico\|Philippines\|Taiwan\|Thailand	1
China\|Germany\|United Kingdom	1
China\|Greece\|Italy	1
China\|Hong Kong\|Japan\|Korea, Republic of\|Philippines\|Taiwan\|Thailand	1
China\|Hong Kong\|Korea, Republic of\|Philippines\|Singapore\|Taiwan\|Thailand	1
China\|India\|Thailand	1
China\|Japan\|Korea, Republic of\|Malaysia\|Philippines\|Taiwan	1
China\|Korea, Republic of	1
China\|Malaysia\|Philippines	1
China\|Taiwan\|Thailand	1
China\|Turkey	1
Colombia\|Ecuador	1
Colombia\|Ecuador\|Hong Kong\|Indonesia\|Malaysia\|Philippines\|Singapore\|Taiwan\|Thailand\|Turkey\|	1
Colombia\|Finland\|Germany\|Guatemala\|Korea, Republic of\|Philippines\|Poland\|Romania\|Russian Federation\|Singapore	1
Colombia\|Germany\|Hungary\|Italy\|Japan\|Mexico\|Poland\|Taiwan\|Turkey	1
Colombia\|Mexico	1
Costa Rica\|Croatia\|Czech Republic\|Dominican Republic\|Indonesia\|Jordan\|Korea, Republic of\|Kuwait\|Lebanon\|Malaysia\|Mexico\|Panama\|Philippines\|Russian Federation\|Saudi Arabia\|Taiwan\|Thailand\|Turkey\|United Arab Emirates\|Venezuela	1
Croatia	1
Croatia\|Georgia\|Hungary\|Serbia\|Slovenia	1
Czech Republic\|Finland\|France\|Germany\|Hungary\|Italy\|Poland\|Slovakia\|Spain\|Sweden	1
Czech Republic\|France\|Germany\|Hong Kong\|Korea, Republic of\|Netherlands\|Russian Federation\|Slovakia\|South Africa\|Sweden\|Taiwan\|Ukraine	1
Czech Republic\|France\|Germany\|Hungary\|Italy\|Lithuania\|Poland\|Portugal\|Serbia\|Sweden\|Switzerland\|Turkey	1
Czech Republic\|Germany\|Latvia\|Netherlands\|Poland\|Switzerland	1
Czech Republic\|Hungary\|Singapore\|United Kingdom	1
Czech Republic\|Italy\|New Zealand\|Spain	1
Czech Republic\|New Zealand	1
Czechia\|Poland	1
Denmark\|Belgium\|Canada\|Finland\|France\|Korea, Republic of\|Netherlands\|Norway\|Philippines\|South Africa\|Sweden\|Taiwan	1
Denmark\|Finland\|Netherlands\|Norway\|Sweden\|United Kingdom	1
Ecuador	1
Egypt\|Hong Kong\|India\|Indonesia\|Korea, Republic of\|Malaysia\|Morocco\|Pakistan\|Philippines\|Singapore\|Taiwan\|Thailand\|Tunisia\|Vietnam	1
Estonia	1
Estonia\|France\|Iceland\|India\|Italy\|Korea, Republic of\|Lithuania\|Spain\|Venezuela	1
Estonia\|France\|Italy\|Norway\|Poland	1
Estonia\|Germany\|Spain	1
Ethiopia	1
Finland\|Germany	1
Finland\|Hungary\|Norway\|United Kingdom	1
Finland\|Sweden	1
Finland\|United States\|Argentina\|Canada\|Denmark\|France\|Germany\|Hungary\|Italy\|Latvia\|Lithuania\|Netherlands\|Poland\|Russian Federation\|Slovakia\|Spain\|Sweden\|Taiwan	1
France\|Austria\|Belgium\|Germany\|Italy\|Netherlands\|Portugal\|Switzerland\|United Kingdom	1
France\|Belarus\|Ukraine	1
France\|Germany	1
France\|Germany\|Greece\|Italy\|Sweden	1
France\|Hungary\|Romania\|Slovakia	1
France\|Italy\|Korea, Republic of\|Poland\|Thailand	1
France\|Italy\|Spain	1
France\|Tunisia	1
Germany\|	1
Germany\|Australia\|Austria\|Belgium\|France\|Latvia\|Poland\|Spain\|Switzerland\|United Kingdom	1
Germany\|Belgium\|Czechia\|France\|Hungary\|Israel\|Italy\|Poland\|Spain\|United Kingdom	1
Germany\|Hungary\|Spain\|Switzerland	1
Germany\|Italy\|Mexico\|Netherlands\|Poland	1
Germany\|Netherlands\|Sweden	1
Germany\|Netherlands\|Switzerland	1
Germany\|Philippines\|Romania\|Russian Federation\|Singapore\|Spain	1
Germany\|Russian Federation\|United Kingdom	1
Germany\|Switzerland\|United Kingdom	1
Germany\|Ukraine	1
Greece\|Italy	1
Greece\|Netherlands	1
Greece\|Slovenia	1
Greece\|United Kingdom	1
Guatemala	1
Honduras\|Mexico	1
India\|Korea, Republic of\|Philippines\|Taiwan	1
Israel\|Serbia	1
Israel\|United States\|Belgium\|Canada\|France\|Germany\|Italy\|Netherlands\|Portugal\|Spain\|Sweden\|United Kingdom	1
Italy\|Lithuania\|Netherlands\|Bulgaria\|Estonia\|France\|Germany\|Hungary\|Poland\|Serbia\|Slovakia\|Spain\|Sweden\|United Kingdom	1
Italy\|Spain	1
Italy\|Spain\|United Kingdom\|	1
Italy\|Venezuela	1
Japan\|Korea, Republic of	1
Japan\|United States\|Australia\|Austria\|Belgium\|Canada\|France\|Germany\|Greece\|Italy\|Netherlands\|Spain\|Sweden\|United Kingdom	1
Latvia	1
Lesotho	1
Lesotho\|Switzerland\|Tanzania	1
Netherlands\|Argentina\|Czech Republic\|Germany\|Iceland\|Italy\|Poland\|Slovakia	1
Netherlands\|Austria\|Belgium\|Bulgaria\|Czechia\|Denmark\|France\|Germany\|Poland\|Romania\|Russian Federation\|Slovakia\|Spain\|Ukraine	1
Netherlands\|Belgium\|Germany\|Slovakia	1
Netherlands\|Denmark\|Estonia\|Former Serbia and Montenegro\|France\|Germany\|Lithuania\|Poland\|Sweden\|Ukraine\|United Kingdom	1
Netherlands\|Spain	1
New Zealand	1
Slovakia	1
Slovakia\|Belgium\|Bulgaria\|Czechia\|Denmark\|Germany\|Hungary\|Italy\|Latvia\|Netherlands\|Poland\|Romania\|Russian Federation\|Spain\|Ukraine	1
Sweden\|United States\|Argentina\|Australia\|Austria\|Belarus\|Belgium\|Canada\|Chile\|China\|Colombia\|Czechia\|Denmark\|France\|Germany\|Greece\|Hungary\|India\|Ireland\|Israel\|Italy\|Korea, Republic of\|Malaysia\|Mexico\|Netherlands\|Peru\|Poland\|Romania\|Russian Federation\|Serbia\|Singapore\|Slovakia\|Spain\|Switzerland\|Taiwan\|Thailand\|Turkey\|Ukraine\|United Kingdom	1
Taiwan\|Turkey\|United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Canada\|China\|Czech Republic\|Denmark\|France\|Germany\|Ireland\|Israel\|Italy\|Japan\|Korea, Republic of\|Mexico\|Netherlands\|Poland\|Portugal\|Russian Federation\|Slovakia\|Spain\|Switzerland\|United Kingdom	1
Tanzania	1
Tunisia	1
Turkey\|	1
United Kingdom\|Austria\|Germany\|Netherlands\|Poland	1
United States\|Argentina\|Australia\|Austria\|Belarus\|Belgium\|Brazil\|Canada\|China\|Colombia\|Czechia\|Denmark\|France\|Germany\|Hungary\|Israel\|Italy\|Korea, Republic of\|Malaysia\|Mexico\|Netherlands\|Norway\|Poland\|Portugal\|Romania\|Russian Federation\|Serbia\|Singapore\|Slovakia\|Spain\|Sweden\|Taiwan\|Thailand\|Turkey\|Ukraine\|United Kingdom\|Vietnam	1
United States\|Argentina\|Australia\|Austria\|Belarus\|Belgium\|Bulgaria\|Canada\|Chile\|China\|Colombia\|Croatia\|Finland\|France\|Germany\|Hong Kong\|Hungary\|India\|Israel\|Italy\|Malaysia\|Mexico\|Netherlands\|Peru\|Poland\|Romania\|Russian Federation\|Serbia\|Singapore\|Slovakia\|South Africa\|Sweden\|Taiwan\|Thailand\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belarus\|Belgium\|Bulgaria\|Canada\|Chile\|China\|Colombia\|Croatia\|France\|Germany\|Hong Kong\|Hungary\|India\|Israel\|Italy\|Malaysia\|Mexico\|Netherlands\|Norway\|Peru\|Poland\|Romania\|Russian Federation\|Serbia\|Singapore\|Slovakia\|South Africa\|Spain\|Sweden\|Taiwan\|Thailand\|Turkey\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Bulgaria\|Canada\|China\|Czechia\|Denmark\|Germany\|Hungary\|Israel\|Italy\|Korea, Republic of\|Mexico\|Netherlands\|Poland\|Portugal\|Russian Federation\|Singapore\|Slovakia\|Spain\|Sweden\|Switzerland\|Taiwan\|Thailand\|Turkey\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Canada\|China\|Czech Republic\|Denmark\|France\|Germany\|Greece\|Ireland\|Israel\|Italy\|Japan\|Korea, Republic of\|Mexico\|Netherlands\|New Zealand\|Poland\|Portugal\|Russian Federation\|Singapore\|Spain\|Sweden\|Switzerland\|Taiwan\|Thailand\|Turkey\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Canada\|China\|Czechia\|Denmark\|France\|Germany\|Greece\|Italy\|Japan\|Korea, Republic of\|Mexico\|Poland\|Portugal\|Russian Federation\|Singapore\|Sweden\|Switzerland\|Taiwan\|Thailand\|Turkey\|United Kingdom	1
United States\|Argentina\|Australia\|Austria\|Belgium\|Brazil\|Canada\|China\|Czechia\|Denmark\|France\|Germany\|Israel\|Italy\|Japan\|Korea, Republic of\|Mexico\|Poland\|Portugal\|Russian Federation\|Slovakia\|Spain\|Switzerland\|Taiwan\|Turkey\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Brazil\|Bulgaria\|Canada\|China\|Croatia\|Czechia\|Denmark\|France\|Greece\|Hungary\|Israel\|Italy\|Korea, Republic of\|Poland\|Romania\|Singapore\|Spain\|Sweden\|Taiwan\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Brazil\|Bulgaria\|Canada\|China\|Croatia\|Czechia\|Denmark\|France\|Greece\|Hungary\|Israel\|Italy\|Korea, Republic of\|Poland\|Romania\|Singapore\|Spain\|Taiwan\|Ukraine\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Brazil\|Canada\|Czechia\|Germany\|Israel\|Japan\|Mexico\|Netherlands\|Philippines\|Spain\|United Kingdom	1
United States\|Argentina\|Australia\|Belgium\|Brazil\|Denmark\|France\|Germany\|New Zealand\|Spain	1
United States\|Argentina\|Australia\|Brazil\|Canada\|Chile\|Colombia\|Estonia\|Hungary\|Israel\|Jordan\|Netherlands\|New Zealand\|Poland\|United Kingdom	1
United States\|Argentina\|Australia\|Brazil\|Canada\|Chile\|Mexico\|Russian Federation\|Ukraine	1
United States\|Argentina\|Australia\|Canada\|Colombia\|Denmark\|Finland\|Greece\|Italy\|Mexico\|Panama\|Peru\|Romania\|Russian Federation\|South Africa\|Spain\|Sweden\|Taiwan	1
United States\|Argentina\|Australia\|Canada\|Korea, Republic of\|Mexico\|New Zealand\|Taiwan	1
United States\|Argentina\|Austria\|Belgium\|Brazil\|Canada\|Colombia\|Czechia\|Denmark\|Egypt\|France\|Germany\|Hong Kong\|Israel\|Italy\|Korea, Republic of\|New Zealand\|Peru\|Philippines\|Poland\|Russian Federation\|Singapore\|South Africa\|Spain\|Turkey\|United Kingdom	1
United States\|Argentina\|Belgium\|Brazil\|Canada\|Italy\|Korea, Republic of\|Lithuania\|Russian Federation\|South Africa\|Spain\|Ukraine\|United Kingdom	1
United States\|Argentina\|Brazil\|Bulgaria\|Colombia\|Hungary\|Italy\|Mexico\|Poland\|South Africa\|Turkey\|Ukraine	1
United States\|Argentina\|Brazil\|Canada\|Chile\|Germany\|Greece\|Hong Kong\|Italy\|Korea, Republic of\|Malaysia\|Mexico\|Netherlands\|Poland\|Portugal\|Russian Federation\|Singapore\|South Africa\|Spain\|Taiwan\|Turkey	1
United States\|Argentina\|Brazil\|Canada\|Denmark\|France\|Germany\|Italy\|Spain\|Sweden\|United Kingdom	1
United States\|Argentina\|Brazil\|Chile\|Colombia\|India\|Kenya\|Peru\|South Africa\|Uganda\|Zambia	1
United States\|Argentina\|Brazil\|Mexico\|South Africa	1
United States\|Argentina\|Canada\|Chile\|Mexico\|Peru	1
United States\|Argentina\|Canada\|Colombia\|Czechia\|Egypt\|Germany\|Italy\|Korea, Republic of\|Malaysia\|New Zealand\|Singapore\|South Africa\|Turkey\|United Kingdom	1
United States\|Argentina\|Canada\|Germany\|Romania\|Slovakia\|Spain\|Taiwan\|Vietnam	1
United States\|Argentina\|Canada\|Hungary\|India\|Korea, Republic of\|Romania\|Slovakia\|Spain	1
United States\|Argentina\|Colombia\|Finland\|Germany\|Italy\|Russian Federation\|Spain\|Sweden	1
United States\|Argentina\|Colombia\|France\|Germany\|Greece\|Italy\|Japan\|Korea, Republic of\|Russian Federation\|Spain\|Taiwan	1
United States\|Argentina\|Colombia\|France\|Germany\|India\|Spain	1
United States\|Argentina\|Ecuador\|Germany\|Guatemala\|Italy\|Switzerland\|Turkey	1
United States\|Argentina\|France\|Germany\|Hungary\|Italy\|Japan\|Russian Federation\|Spain	1
United States\|Argentina\|Guatemala\|Philippines\|Puerto Rico\|Russian Federation\|Spain	1
United States\|Argentina\|Korea, Republic of\|Mexico\|Netherlands\|Slovakia\|South Africa\|Spain\|Sweden	1
United States\|Argentina\|Mexico\|Peru	1
United States\|Australia	1
United States\|Australia\|Austria\|Belgium\|Brazil\|Denmark\|Hong Kong\|Hungary\|Israel\|Peru\|Philippines\|Poland\|Spain\|Taiwan	1
United States\|Australia\|Austria\|Belgium\|Canada\|China\|Czech Republic\|France\|Germany\|Italy\|Netherlands\|Spain\|Switzerland\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Canada\|China\|Czechia\|Denmark\|France\|Germany\|Italy\|Japan\|Netherlands\|Poland\|Singapore\|Spain\|Switzerland\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Canada\|Denmark\|France\|Germany\|Ireland\|Italy\|Netherlands\|Spain\|Sweden\|Switzerland\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Canada\|France\|Germany\|India\|Ireland\|Israel\|Italy\|Mexico\|Netherlands\|Poland\|Portugal\|Puerto Rico\|Spain\|Sweden\|United Kingdom	1
United States\|Australia\|Austria\|Belgium\|Canada\|France\|Germany\|Ireland\|Israel\|Italy\|Netherlands\|Poland\|Spain\|United Kingdom	1
United States\|Australia\|Austria\|Canada\|China\|Colombia\|Finland\|France\|Hungary\|Israel\|Korea, Republic of\|Malaysia\|Mexico\|Philippines\|Poland\|Portugal\|Russian Federation\|South Africa\|Spain\|Thailand\|Ukraine\|Vietnam	1
United States\|Australia\|Austria\|Canada\|Germany\|Greece\|Ireland\|Japan\|United Kingdom	1
United States\|Australia\|Austria\|Canada\|Germany\|Greece\|Japan\|United Kingdom	1
United States\|Australia\|Belarus\|Belgium\|Brazil\|Bulgaria\|Canada\|Colombia\|Denmark\|France\|Germany\|Hungary\|Israel\|Italy\|Korea, Republic of\|Lithuania\|Malaysia\|Mexico\|Poland\|Portugal\|Romania\|Russian Federation\|Serbia\|Spain\|Sweden\|Switzerland\|Taiwan\|Thailand\|Turkey\|Ukraine\|Vietnam	1
United States\|Australia\|Belarus\|China\|Czechia\|France\|Germany\|Hungary\|India\|Israel\|Italy\|Mexico\|Netherlands\|Poland\|Russian Federation\|Serbia\|South Africa\|Spain\|Ukraine	1
United States\|Australia\|Belarus\|China\|Czechia\|France\|Germany\|Hungary\|India\|Israel\|Italy\|Mexico\|Poland\|Russian Federation\|Serbia\|South Africa\|Spain\|Ukraine	1
United States\|Australia\|Belgium\|Bosnia and Herzegovina\|Croatia\|Czechia\|Germany\|Greece\|Hong Kong\|Israel\|Latvia\|Malaysia\|Mexico\|Poland\|Romania\|Russian Federation\|Serbia\|Singapore\|South Africa\|Spain\|Thailand\|Turkey\|Ukraine	1
United States\|Australia\|Belgium\|Brazil\|Canada\|Germany\|Israel\|Philippines\|Singapore\|Spain	1
United States\|Australia\|Belgium\|Brazil\|Czech Republic\|Denmark\|France\|Germany\|Hong Kong\|Hungary\|Israel\|Italy\|Korea, Republic of\|Malaysia\|Mexico\|Netherlands\|Norway\|Poland\|Singapore\|South Africa\|Spain\|Sweden\|United Kingdom	1
United States\|Australia\|Belgium\|Brazil\|Czech Republic\|Denmark\|France\|Germany\|Hong Kong\|Hungary\|Israel\|Italy\|Korea, Republic of\|Malaysia\|Mexico\|Netherlands\|Poland\|Singapore\|South Africa\|Spain\|Sweden\|United Kingdom	1
United States\|Australia\|Belgium\|Canada\|China\|Czechia\|Denmark\|Finland\|France\|Germany\|Greece\|Hungary\|Israel\|Italy\|Korea, Republic of\|Lithuania\|Netherlands\|Poland\|Russian Federation\|Spain\|Ukraine\|United Kingdom	1
United States\|Australia\|Belgium\|France\|Germany\|Italy	1
United States\|Australia\|Belgium\|Germany\|Italy\|Lithuania\|United Kingdom	1
United States\|Australia\|Brazil\|Bulgaria\|Canada\|Czechia\|Germany\|Hungary\|Italy\|Japan\|Malaysia\|Mexico\|Poland\|Russian Federation\|South Africa\|Spain\|Taiwan\|Turkey	1
United States\|Australia\|Brazil\|Czech Republic\|Hungary	1
United States\|Australia\|Brazil\|France\|Germany\|Israel\|Spain\|United Kingdom	1
United States\|Australia\|Bulgaria\|Czechia\|Hungary\|Poland\|Romania\|Serbia\|Slovakia\|Spain	1
United States\|Australia\|Bulgaria\|Czechia\|Hungary\|Poland\|Romania\|Serbia\|Spain	1
United States\|Australia\|Canada\|Colombia\|Czech Republic\|Denmark\|Finland\|Germany\|Hungary\|India\|Ireland\|Mexico\|Poland\|Puerto Rico\|Romania\|United Kingdom	1
United States\|Australia\|Canada\|Denmark\|Estonia\|Germany\|Israel\|New Zealand\|Philippines\|Poland\|Russian Federation\|United Kingdom	1
United States\|Australia\|Canada\|Denmark\|Germany\|Israel\|Italy\|Latvia\|Lithuania\|Romania\|Sweden\|Turkey	1
United States\|Australia\|Czech Republic\|France\|Germany\|Greece\|Israel\|Italy\|Taiwan\|United Kingdom	1
United States\|Australia\|Czech Republic\|Germany\|Hungary\|Israel\|Russian Federation\|Spain\|United Kingdom	1
United States\|Australia\|France\|Germany\|Hong Kong\|Israel\|Italy\|Malaysia\|Netherlands\|Russian Federation\|Singapore\|United Kingdom	1
United States\|Australia\|France\|New Zealand\|Spain	1
United States\|Austria\|Belgium\|Brazil\|Canada\|Czechia\|Denmark\|France\|Germany\|Greece\|Italy\|Japan\|Korea, Republic of\|Mexico\|Netherlands\|Poland\|Portugal\|Spain\|Taiwan\|Turkey\|United Kingdom	1
United States\|Austria\|Belgium\|Brazil\|France\|Germany\|Israel\|Italy\|Japan\|Mexico\|Netherlands\|Poland\|Spain\|Turkey	1
United States\|Austria\|Belgium\|Canada\|China\|France\|India\|Israel\|Italy\|Mexico\|Netherlands\|Poland\|Puerto Rico	1
United States\|Austria\|Belgium\|Canada\|Czechia\|France\|Germany\|Israel\|Italy\|Spain\|Switzerland	1
United States\|Austria\|Belgium\|Canada\|France\|Germany\|Italy\|Japan\|Korea, Republic of\|Netherlands\|Spain\|Sweden\|Switzerland\|United Kingdom	1
United States\|Austria\|Belgium\|France\|Germany\|Ireland\|Israel\|Italy\|Spain\|United Kingdom	1
United States\|Austria\|Bulgaria\|Chile\|China\|France\|Germany\|Greece\|Israel\|Malaysia\|Mexico\|Philippines\|Poland\|Portugal\|Romania\|Russian Federation\|Serbia\|Spain\|Turkey\|United Kingdom\|Vietnam	1
United States\|Austria\|Canada\|Germany	1
United States\|Austria\|Czech Republic\|Germany\|Italy\|New Zealand\|Poland\|Spain\|United Kingdom	1
United States\|Austria\|France\|Germany\|Ireland\|Norway\|Portugal\|Sweden\|Switzerland\|United Kingdom	1
United States\|Austria\|Germany\|United Kingdom	1
United States\|Belarus\|Canada\|China\|France\|Germany\|Hungary\|Israel\|Malaysia\|Poland\|Russian Federation\|Serbia\|Taiwan\|Ukraine\|United Kingdom	1
United States\|Belgium\|Brazil\|France\|Hungary\|India\|Italy\|Poland\|South Africa\|Sweden\|Turkey	1
United States\|Belgium\|Brazil\|France\|Hungary\|India\|Italy\|Poland\|South Africa\|Turkey	1
United States\|Belgium\|Brazil\|Hungary\|Poland	1
United States\|Belgium\|Canada\|Czech Republic\|Denmark\|France\|Israel\|Italy\|Netherlands\|Spain\|United Kingdom	1
United States\|Belgium\|Canada\|Czechia\|France\|Germany\|Italy\|Switzerland\|United Kingdom	1
United States\|Belgium\|Canada\|Denmark\|France\|Germany\|Italy\|Netherlands\|Norway\|Spain\|Sweden\|United Kingdom	1
United States\|Belgium\|Canada\|France\|Germany\|Ireland\|Italy\|Japan\|Spain\|United Kingdom	1
United States\|Belgium\|Canada\|France\|Germany\|Israel\|Netherlands\|Russian Federation	1
United States\|Belgium\|Canada\|Germany\|Italy\|Netherlands\|Peru\|Russian Federation\|Switzerland\|United Kingdom	1
United States\|Belgium\|Canada\|Germany\|Poland\|United Kingdom	1
United States\|Belgium\|Czech Republic\|Germany\|Ireland\|Romania	1
United States\|Belgium\|Czechia\|Germany\|Ireland\|Romania	1
United States\|Belgium\|Denmark\|Finland\|Germany\|Iceland\|India\|Switzerland	1
United States\|Belgium\|Denmark\|France\|Germany\|Italy\|Poland\|Puerto Rico\|Ukraine\|United Kingdom	1
United States\|Belgium\|Denmark\|France\|Italy\|Poland\|Russian Federation\|Singapore\|Spain\|Thailand	1
United States\|Belgium\|Egypt\|Germany\|Poland\|Slovakia\|Spain\|Turkey	1
United States\|Belgium\|France\|Germany\|Hungary\|India\|Italy\|Poland\|Slovakia\|Sweden\|Turkey	1
United States\|Belgium\|France\|Germany\|Hungary\|India\|Italy\|Poland\|Turkey	1
United States\|Belgium\|France\|Germany\|Ireland\|Netherlands\|Switzerland\|United Kingdom	1
United States\|Belgium\|France\|Germany\|Netherlands\|Poland\|United Kingdom	1
United States\|Belgium\|Germany\|Guatemala\|Hungary\|Poland\|Puerto Rico\|Slovakia\|Turkey	1
United States\|Belgium\|Germany\|Netherlands\|Spain\|United Kingdom	1
United States\|Belgium\|Romania\|Spain\|Sweden\|Switzerland\|Ukraine	1
United States\|Brazil\|Canada\|Chile\|Colombia\|Guatemala\|Hungary\|India\|Italy\|Japan\|Malaysia\|Mexico\|Peru\|Poland\|Russian Federation\|Sweden\|Taiwan	1
United States\|Brazil\|Chile\|Colombia\|Guatemala\|Hungary\|India\|Italy\|Japan\|Malaysia\|Mexico\|Poland\|Russian Federation\|Sweden\|Taiwan	1
United States\|Brazil\|Czech Republic\|Denmark\|Germany\|Greece\|Portugal\|Saudi Arabia\|Slovakia\|Spain\|Sweden\|United Kingdom	1
United States\|Brazil\|Czechia\|France\|Germany\|Spain\|United Kingdom	1
United States\|Bulgaria\|China\|France\|Georgia\|Korea, Republic of\|Romania\|Russian Federation	1
United States\|Bulgaria\|Croatia\|Georgia\|Germany\|Hungary\|South Africa\|Ukraine\|United Kingdom	1
United States\|Bulgaria\|Czech Republic\|France\|Hungary\|Korea, Republic of\|Romania\|Russian Federation\|Slovakia\|Spain\|Ukraine	1
United States\|Bulgaria\|Czech Republic\|Hungary	1
United States\|Bulgaria\|Czechia\|Denmark\|France\|Germany\|Hungary\|Ireland\|Italy\|Poland\|South Africa\|Sweden\|United Kingdom	1
United States\|Canada\|Chile\|Ecuador\|Mexico\|Peru\|Spain	1
United States\|Canada\|Colombia\|Czech Republic\|Denmark\|Finland\|Germany\|Hungary\|India\|Mexico\|Peru\|Poland\|Puerto Rico\|Romania\|Russian Federation\|Spain	1
United States\|Canada\|Denmark\|France\|Germany\|Greece\|Italy\|Netherlands\|Romania\|Russian Federation\|Spain\|United Kingdom	1
United States\|Canada\|France\|Germany\|Italy\|Netherlands\|Spain\|United Kingdom	1
United States\|Canada\|France\|Germany\|Russian Federation	1
United States\|Canada\|France\|Poland\|Spain\|United Kingdom	1
United States\|Canada\|Israel\|Puerto Rico	1
United States\|Canada\|Italy\|Puerto Rico\|Slovakia\|Spain\|Taiwan	1
United States\|Canada\|Netherlands	1
United States\|Chile\|Mexico\|Peru	1
United States\|Chile\|Mexico\|Peru\|Russian Federation	1
United States\|China	1
United States\|Czechia\|Russian Federation	1
United States\|Denmark\|France\|Germany\|Netherlands\|Switzerland	1
United States\|Dominican Republic\|India\|Russian Federation\|South Africa	1
United States\|Estonia\|Germany\|Spain	1
United States\|France\|Germany	1
United States\|France\|Germany\|Netherlands\|United Kingdom	1
United States\|France\|Italy	1
United States\|France\|Netherlands\|Spain\|United Kingdom	1
United States\|France\|Spain\|Switzerland	1
United States\|Germany\|Greece\|Italy\|Netherlands\|United Kingdom	1
United States\|Germany\|Netherlands	1
United States\|Greece\|Russian Federation	1
United States\|Guatemala\|Hungary\|Poland\|Puerto Rico\|Slovakia\|Turkey	1
United States\|Hong Kong\|Korea, Republic of\|Singapore\|Taiwan	1
United States\|India	1
United States\|India\|Russian Federation	1
United States\|Japan	1
United States\|Portugal	1
United States\|Singapore	1
United States\|Spain\|United Kingdom	1
Venezuela	1
Zambia	1

Sites per Study

Site_count	Study_Count
1	1935
2	177
3	81
4	49
5	39
6	29
7	30
8	36
9	27
10	25
11	17
12	22
13	17
14	11
15	18
16	17
17	14
18	12
19	5
20	8
21	7
22	6
23	5
24	8
25	7
26	7
27	5
28	4
29	6
30	9
31	5
32	5
33	3
34	7
35	3
36	5
37	3
38	7
39	4
40	6
41	7
42	2
43	5
44	4
45	3
46	7
47	5
48	5
50	5
51	3
52	2
53	4
54	4
55	3
56	1
57	3
58	4
59	2
60	2
61	1
62	2
63	2
64	2
65	4
67	1
68	2
69	2
72	3
73	2
74	2
75	5
76	1
77	1
78	3
79	2
80	2
81	2
82	1
83	2
85	1
86	1
87	1
88	2
90	3
91	1
92	4
93	1
94	1
95	1
96	1
97	2
98	1
99	3
100	1
102	4
106	2
108	1
111	1
113	4
115	1
117	1
118	1
119	2
120	1
122	1
126	3
128	1
129	1
130	2
131	2
133	1
134	2
135	1
136	1
137	1
139	1
141	1
143	1
147	1
148	1
151	1
152	1
153	1
155	1
157	2
158	1
176	1
177	1
178	1
182	2
211	1
232	1
246	1
270	1
298	1
329	1
384	1
413	1

Phase

Phase	Study_Count
N/A	996
Phase 3	630
Phase 4	547
Phase 2	376
Phase 1	219
Phase 1/Phase 2	50
Phase 2/Phase 3	43
Early Phase 1	16

Number of Arms

Number_of_Arms	Count_of_Studies
1	485
2	1384
3	328
4	167
5	44
6	42
7	12
8	12
9	6
10	3
11	1
12	1
14	2
15	1
16	2
24	1
NA	386

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	5.00	2.0000	2.00000	6.00	3.0000	12.0000	2.0000	2.0000
1st Qu.	10.00	38.0000	24.00000	23.25	32.0000	39.0000	129.0000	50.0000
Median	24.50	83.0000	34.00000	57.50	70.0000	80.0000	288.0000	124.0000
Mean	188.50	637.0354	55.36406	104.24	125.0691	307.0465	484.0609	552.6753
3rd Qu.	104.25	238.0000	60.00000	106.75	135.7500	248.0000	601.7500	358.5000
Max.	1545.00	66570.0000	500.00000	1000.00	1659.0000	4000.0000	13500.0000	40000.0000

Trial Group Type

group_type	Group_Count
Experimental	3027
Active Comparator	1511
Placebo Comparator	562
NA	386
No Intervention	349
Other	245
Sham Comparator	69

Intervention Model

intervention_model	Study_Count
Parallel Assignment	1797
Single Group Assignment	597
Crossover Assignment	359
Factorial Assignment	68
NA	37
Sequential Assignment	19

Primary Purpose

primary_purpose	Study_Count
Treatment	2142
Prevention	237
Diagnostic	101
Health Services Research	96
NA	75
Basic Science	71
Other	68
Supportive Care	61
Screening	22
Device Feasibility	2
Educational/Counseling/Training	2

Observational Studies

Studies by Country

Country	Study_Count
United States	151
NA	132
China	29
France	27
Canada	23
Korea, Republic of	21
Germany	20
United Kingdom	15
Japan	14
Austria	13
Switzerland	13
Denmark	12
Italy	10
Russian Federation	9
Spain	9
Poland	8
Greece	7
Netherlands	7
Taiwan	7
Egypt	6
Hong Kong	6
Turkey	6
Belgium	5
Israel	5
Sweden	5
South Africa	4
Brazil	3
India	3
Mexico	3
Nigeria	3
Portugal	3
Romania	3
Thailand	3
United States\|Puerto Rico	3
Argentina	2
Egypt\|Saudi Arabia\|United Arab Emirates	2
Finland	2
Norway	2
Singapore	2
Uganda	2
Algeria	1
Algeria\|Egypt\|Lebanon\|Saudi Arabia\|United Arab Emirates	1
Argentina\|Australia\|Austria\|Belgium\|Canada\|Colombia\|Czechia\|Denmark\|Estonia\|Finland\|France\|Germany\|Greece\|Ireland\|Italy\|Luxembourg\|Netherlands\|Norway\|Portugal\|Russian Federation\|Saudi Arabia\|Slovakia\|Spain\|Sweden\|Switzerland\|Taiwan\|Turkey\|United Kingdom	1
Armenia\|Austria\|Belgium\|Bulgaria\|Croatia\|Czechia\|Estonia\|Germany\|Greece\|Israel\|Italy\|Lebanon\|Lithuania\|Netherlands\|Poland\|Portugal\|Romania\|Serbia\|Spain\|Sweden\|Ukraine\|United Kingdom	1
Australia	1
Australia\|Austria\|Finland\|France\|Germany\|Greece\|Italy\|Netherlands\|New Zealand\|Norway\|Spain\|Sweden\|United Kingdom	1
Austria\|Belgium\|France\|Germany\|Greece\|Norway\|Russian Federation\|Spain\|Sweden\|Switzerland\|Turkey\|United Kingdom	1
Austria\|Germany\|Greece\|Italy\|Spain\|Switzerland\|United Kingdom	1
Austria\|Germany\|Switzerland	1
Bahrain\|Egypt\|Jordan\|Lebanon\|Morocco\|Oman\|Pakistan\|Qatar\|Russian Federation\|Saudi Arabia\|United Arab Emirates	1
Belgium\|Canada\|Colombia\|Czechia\|Ecuador\|Indonesia\|Jordan\|Lebanon\|Mexico\|Turkey\|Venezuela\|Yemen	1
Belgium\|Canada\|Colombia\|Germany\|Japan\|Sweden\|Turkey	1
Belgium\|Estonia\|Italy\|Portugal\|Spain\|United Kingdom	1
Belgium\|Germany\|Ireland\|Italy\|Switzerland	1
Colombia	1
Croatia	1
Croatia\|Czech Republic	1
Croatia\|Poland\|Slovakia\|Slovenia	1
Czech Republic	1
Czechia	1
Ecuador	1
France\|Germany\|Italy\|Portugal\|Spain\|United Kingdom	1
France\|Italy\|Netherlands\|United Kingdom	1
Germany\|Ireland	1
Germany\|Netherlands	1
Germany\|Switzerland	1
Kazakhstan\|Kyrgyzstan\|Lebanon\|Russian Federation\|Saudi Arabia\|Turkey	1
Kazakhstan\|Russian Federation	1
Kyrgyzstan	1
Latvia	1
Malaysia	1
Mali	1
Poland\|Slovakia	1
Romania\|Slovakia	1
Serbia	1
Slovakia	1
Slovenia	1
Tunisia	1
United States\|Brazil	1
United States\|Canada	1
United States\|Canada\|Chile\|Ecuador\|Mexico\|Peru\|Spain	1
United States\|Canada\|Ireland\|United Kingdom	1
United States\|Canada\|Israel\|Singapore\|United Kingdom	1
United States\|Guatemala\|Hungary\|Poland\|Puerto Rico\|Slovakia\|Turkey	1
United States\|Iceland	1
United States\|Russian Federation	1
Vietnam	1

Sites per Study

Site_count	Study_Count
1	513
2	35
3	9
4	6
5	3
6	4
7	7
8	7
9	1
10	3
11	2
12	4
13	4
15	1
16	1
17	1
18	1
19	1
20	1
21	1
23	3
24	1
25	2
28	1
35	2
39	1
43	1
45	1
46	1
49	1
51	1
52	1
54	1
55	1
56	1
66	1
84	1
88	1
106	1
120	2
132	1
134	1
158	1
167	1
182	1
254	1
314	1
326	1
375	1
436	1
568	1
778	1
915	1
936	1
1300	1
1387	1
2389	1

Enrollment Metrics

Measure	Observational
Min	1.000
1st Qu	80.000
Median	268.000
Mean	8764.711
3rd Qu	1529.250
Max	1400000.000

Observation Model

observational_model	Study_Count
Cohort	340
NA	99
Case-Only	70
Case-Control	43
Case Control	36
Other	36
Case-Crossover	8
Ecologic or Community	8
Family-Based	2
Natural History	2
Case Control, Natural History	1
Defined Population	1
Defined Population, Natural History	1

Time Perspective

time_perspective	Study_Count
Prospective	410
Cross-Sectional	89
Retrospective	79
NA	55
Other	9
Cross-Sectional, Prospective	2
Longitudinal, Prospective	2
Cross-Sectional, Retrospective	1

Registries

Studies by Country

Country	Study_Count
United States	10
China	9
Korea, Republic of	6
NA	6
Poland	5
Brazil	4
Italy	4
Kyrgyzstan	4
Germany	3
Netherlands	3
Spain	3
Turkey	3
United States\|Puerto Rico	3
Denmark	2
Thailand	2
Argentina\|Armenia\|Australia\|Italy\|Kazakhstan\|Mexico\|Portugal\|Romania\|Russian Federation\|Ukraine	1
Austria	1
Belgium\|Netherlands\|Poland	1
Canada	1
Denmark\|Norway\|Sweden	1
Germany\|Netherlands	1
Greece	1
Hong Kong	1
Israel	1
Russian Federation	1
South Africa	1
Sweden	1
Switzerland	1
Taiwan	1
Tunisia	1
Ukraine	1
United States\|Australia\|Austria\|Belgium\|Brazil\|Canada\|Denmark\|Egypt\|Finland\|Germany\|Italy\|Japan\|Korea, Republic of\|Netherlands\|Poland\|Russian Federation\|Slovakia\|Spain\|Switzerland\|Taiwan\|Turkey\|United Kingdom	1
United States\|Australia\|Brazil\|Canada\|China\|Colombia\|France\|Germany\|Hungary\|Israel\|Italy\|Japan\|Mexico\|Netherlands\|Poland\|Saudi Arabia\|Sweden\|Switzerland	1
United States\|Canada	1

Sites per Study

Site_count	Study_Count
1	64
2	3
3	1
4	1
5	1
6	1
8	2
11	1
17	1
19	1
24	1
32	1
38	1
41	1
51	1
52	2
59	1
76	1
85	1

Enrollment Metrics

Measure	Registries
Min	10.000
1st Qu	144.500
Median	390.000
Mean	4740.035
3rd Qu	1283.000
Max	200000.000

Registry Model

observational_model	Study_Count
Cohort	61
Case-Control	11
Case-Only	7
Other	5
Case-Crossover	1
Case Control	1

Time Perspective

time_perspective	Study_Count
Prospective	65
Cross-Sectional	15
Other	5
NA	1

Follow-up

target_duration	Study_Count
5 Years	16
3 Years	10
2 Years	7
10 Years	6
6 Months	5
1 Day	4
4 Years	4
1 Year	3
12 Months	3
20 Years	3
3 Days	3
4 Weeks	3
2 Days	2
2 Weeks	2
4 Months	2
7 Days	2
1 Week	1
10 Months	1
12 Weeks	1
18 Months	1
2 Months	1
21 Days	1
3 Months	1
36 Months	1
60 Days	1
7 Years	1
78 Weeks	1

Overview of Studies

Interventional Trials

#If less then 500 trials

Observational Studiess

#If less then 500 studies

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT04459364	The Prevalence of Pulmonary Hypertension in Patients With COVID-19.	https://ClinicalTrials.gov/show/NCT04459364	Recruiting	Attgeno AB	2020-07-07
NCT03305562	Pediatric Hypertension Registry (PHREG)	https://ClinicalTrials.gov/show/NCT03305562	Enrolling by invitation	Wake Forest University Health Sciences	2027-09-20
NCT03267615	VICIS - Vienna Cirrhosis Study	https://ClinicalTrials.gov/show/NCT03267615	Recruiting	Medical University of Vienna	2026-12-31
NCT03243045	Systemic Microvascular Function in Patients With Resistant Hypertension After Renal Sympathetic Denervation	https://ClinicalTrials.gov/show/NCT03243045	Completed	National Institute of Cardiology, Laranjeiras, Brazil	2020-01-06
NCT03246022	Characteristics of Obstructive Sleep Apnea Syndrome Related Hypertension and the Effect of Continuous Positive Airway Pressure Treatment on Blood Pressure	https://ClinicalTrials.gov/show/NCT03246022	Recruiting	Huai’an No.1 People’s Hospital	2020-12-30
NCT03278002	A Registry for Patients Taking Uptravi	https://ClinicalTrials.gov/show/NCT03278002	Active, not recruiting	Actelion	2022-06-30
NCT03185572	Registry for Chronic Obstructive Pulmonary Disease With Pulmonary Hypertension in China	https://ClinicalTrials.gov/show/NCT03185572	Recruiting	Chinese Academy of Medical Sciences, Fuwai Hospital	2020-12-31
NCT03165656	Right Ventricular Function at Rest in Highlanders/Lowlanders	https://ClinicalTrials.gov/show/NCT03165656	Completed	University of Zurich	2017-08-16
NCT03150888	Multi-provincial Cohort for Hypertension (MUCH)	https://ClinicalTrials.gov/show/NCT03150888	Recruiting	Beijing Institute of Heart, Lung and Blood Vessel Diseases	2020-12-31
NCT03146702	Turkish Translation of The Emphasis-10 Questionnaire	https://ClinicalTrials.gov/show/NCT03146702	Completed	Istanbul University	2017-08-31
NCT03049995	Stress Echo 2020 - The International Stress Echo Study	https://ClinicalTrials.gov/show/NCT03049995	Recruiting	Fatebenefratelli Hospital	2020-12-31
NCT03039972	Changes in Renal Function and Body Composition in Pulmonary Hypertension	https://ClinicalTrials.gov/show/NCT03039972	Active, not recruiting	University of Giessen	2019-10-07
NCT03002558	Long-term Cardiovascular Outcomes in Patients With RH and OSA With or Without Treatment With CPAP	https://ClinicalTrials.gov/show/NCT03002558	Recruiting	Sociedad EspaÃ±ola de NeumologÃa y CirugÃa TorÃ¡cica	2023-06-30
NCT02880631	BAROSTIM THERAPYâ„¢ In Resistant Hypertension	https://ClinicalTrials.gov/show/NCT02880631	Recruiting	CVRx, Inc.	2024-07-31
NCT02777957	Predictors of Pulmonary Hypertension in Patients With Advanced Lung Diseases	https://ClinicalTrials.gov/show/NCT02777957	Active, not recruiting	Silesian Centre for Heart Diseases	2020-04-30
NCT02729844	Neolifes Heart - Pulmonary Hypertension in Preterm Children	https://ClinicalTrials.gov/show/NCT02729844	Recruiting	University Medical Center Groningen	2020-04-30
NCT02655029	Study for the Recording of Adherence to Treatment With Perindopril/Indapamide/Amlodipine Fixed Dose Combination	https://ClinicalTrials.gov/show/NCT02655029	Completed	Servier Hellas Pharmaceuticals Ltd.	2016-12-31
NCT02656238	New International CTEPH Database	https://ClinicalTrials.gov/show/NCT02656238	Completed	International CTEPH Association	2020-01-31
NCT02610660	Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension	https://ClinicalTrials.gov/show/NCT02610660	Recruiting	Association for Pediatric Pulmonary Hypertension	2021-12-31
NCT02577835	International Registry for Ambulatory Blood Pressure and Arterial Stiffness Telemonitoring	https://ClinicalTrials.gov/show/NCT02577835	Recruiting	Italian Institute of Telemedicine	2018-12-31
NCT03045029	ADAPT - A Patient Registry of the Real-world Use of OrenitramÂ®	https://ClinicalTrials.gov/show/NCT03045029	Recruiting	United Therapeutics	2022-06-30
NCT02555137	Early Non-invasive Detection of CTEPH After Pulmonary Embolism	https://ClinicalTrials.gov/show/NCT02555137	Active, not recruiting	Leiden University Medical Center	2019-11-30
NCT02553512	Helius in Hypertension-I: The UK Hypertension Registry	https://ClinicalTrials.gov/show/NCT02553512	Completed	Proteus Digital Health, Inc.	2014-12-31
NCT02534324	The Effect of Pre-discharge Blood Pressure of Patients With Asymptomatic Severe Hypertension in Emergency Department	https://ClinicalTrials.gov/show/NCT02534324	Completed	Chulalongkorn University	2015-12-31
NCT02429284	U.S. CTEPH Registry	https://ClinicalTrials.gov/show/NCT02429284	Completed	University of California, San Diego	2019-05-31
NCT02401854	Prevalence of Sub-Clinical Atrial Fibrillation in Elderly Patients With Hypertension, Detected Using an External Loop Recorder	https://ClinicalTrials.gov/show/NCT02401854	Completed	Population Health Research Institute	2015-03-31
NCT02391441	Ventricular Reversed Remodeling After LTX in PAH Patients	https://ClinicalTrials.gov/show/NCT02391441	Completed	University Medical Center Groningen	2019-08-31
NCT02385721	Post-Authorization Long-term Safety Surveillance on Antihypertensive Treatment With KanarbÂ® (Fimasartan)	https://ClinicalTrials.gov/show/NCT02385721	Completed	Boryung Pharmaceutical Co., Ltd	2017-07-31
NCT02265887	The Pan African Pulmonary Hypertension Cohort Study	https://ClinicalTrials.gov/show/NCT02265887	Completed	University of Cape Town	2013-12-31
NCT02249923	Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry	https://ClinicalTrials.gov/show/NCT02249923	Recruiting	University of Colorado, Denver	2020-12-31
NCT02252705	Mexican Registry of Pulmonary Hypertension	https://ClinicalTrials.gov/show/NCT02252705	Completed	Remehip	2017-12-31
NCT02249806	ZÃ¼rich Pulmonary Hypertension Outcome Assessment Cohort	https://ClinicalTrials.gov/show/NCT02249806	Recruiting	University of Zurich	2024-09-30
NCT02226471	Serum CTRP3 and RBP4 Levels in Obesity and Hypertension	https://ClinicalTrials.gov/show/NCT02226471	Completed	Third Military Medical University	2014-02-28
NCT02211365	Registro Campania Salute Network on Hypertension	https://ClinicalTrials.gov/show/NCT02211365	Recruiting	Federico II University	2017-03-31
NCT02195388	Focus On Stiffness Reduction, Endothelial Function and Autonomic Nervous System	https://ClinicalTrials.gov/show/NCT02195388	Completed	Medical Universtity of Lodz	2014-12-31
NCT03385070	Salt Sensitivity Hypertension and Lens Opacities	https://ClinicalTrials.gov/show/NCT03385070	Completed	Kecioren Education and Training Hospital	2017-12-07
NCT02020174	The Preeclampsia Registry	https://ClinicalTrials.gov/show/NCT02020174	Recruiting	Preeclampsia Foundation	2030-05-31
NCT01977014	NIMS- New Implantable Pump in Pulmonary Arterial Hypertension, a Safety Follow up	https://ClinicalTrials.gov/show/NCT01977014	Completed	NordicInfu Care AB	2016-12-31
NCT01882790	The Prevalence of Coronary Spasm in Hypertensive Patients Treated With Antihypertensive Medication	https://ClinicalTrials.gov/show/NCT01882790	Completed	Korea University	2013-08-31
NCT01861080	Korean Registry of Target Organ Damages in Hypertension	https://ClinicalTrials.gov/show/NCT01861080	Active, not recruiting	Dongtan Sacred Heart Hospital	2021-12-31
NCT01854190	Obstructive Sleep Apnea and Endothelial Function in Patients With Resistant Hypertension	https://ClinicalTrials.gov/show/NCT01854190	Completed	Rio de Janeiro State University	2013-01-31
NCT01833429	Autonomic Dysfunction in Resistant Hypertension	https://ClinicalTrials.gov/show/NCT01833429	Completed	University of Campinas, Brazil	2012-11-30
NCT01799473	Tyvaso Dosing and Titration Evaluation: TyTRATE Registry	https://ClinicalTrials.gov/show/NCT01799473	Completed	United Therapeutics	2014-12-31
NCT01784458	Clinical Significance of Intra-abdominal Hypertension in Surgical Patients With Severe Sepsis	https://ClinicalTrials.gov/show/NCT01784458	Completed	University of Ulsan	2009-10-31
NCT01659411	Adult Congenital Heart Disease Registry (QuERI)	https://ClinicalTrials.gov/show/NCT01659411	Completed	Actelion	2018-05-16
NCT01623492	Eisenmenger Quality Enhancement Research Initiative	https://ClinicalTrials.gov/show/NCT01623492	Completed	Actelion	2018-04-17
NCT01456208	Genetic Mechanisms in Human Hypertension	https://ClinicalTrials.gov/show/NCT01456208	Active, not recruiting	Brigham and Women’s Hospital	2020-06-30
NCT01389206	Pulmonary Arterial Hypertension Quality Enhancement Research Initiative Extension Program	https://ClinicalTrials.gov/show/NCT01389206	Completed	Actelion	2018-04-10
NCT04433416	Hypertension and Controlled Hypotension in the Elderly	https://ClinicalTrials.gov/show/NCT04433416	Recruiting	Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University	2020-12-31
NCT04421183	Investigation of the Serum Mucoprotein 3 (MUC3) Protein Levels in Gestational Hypertensive Disease	https://ClinicalTrials.gov/show/NCT04421183	Completed	Karadeniz Technical University	2011-01-01
NCT04374110	Drug Safety and the Occurrence of Complications During Hospitalization in Patients With COVID-19	https://ClinicalTrials.gov/show/NCT04374110	Recruiting	Institute of Cardiology, Warsaw, Poland	2020-06-24
NCT04364984	ARB, ACEi, DRi in COVID-19	https://ClinicalTrials.gov/show/NCT04364984	Recruiting	Medical Practice Prof D. Ivanov	2021-04-01
NCT04331574	Renin-Angiotensin System Inhibitors and COVID-19	https://ClinicalTrials.gov/show/NCT04331574	Recruiting	Societa Italiana dell’Ipertensione Arteriosa	2020-04-10
NCT04314557	Renal Arterial Denervation in Sympathetic Dysautonomia	https://ClinicalTrials.gov/show/NCT04314557	Recruiting	St Carlos Hospital, Madrid, Spain	2020-12-31
NCT04298944	Association of Mood With Risk for Atherosclerosis	https://ClinicalTrials.gov/show/NCT04298944	Recruiting	Johns Hopkins University	2020-08-01
NCT04235829	Does Early Weight Loss Following Laparoscopic Sleeve Gastrectomy Affect Long-term Outcomes	https://ClinicalTrials.gov/show/NCT04235829	Completed	Shaare Zedek Medical Center	2012-10-01
NCT04160533	Registry of Arterial Hypertension	https://ClinicalTrials.gov/show/NCT04160533	Recruiting	Federal State Budgetary Scientific Institution, Research Institute of Cardiology	2020-12-31
NCT04145024	Giessen Pulmonary Hypertension Registry and Biobank	https://ClinicalTrials.gov/show/NCT04145024	Recruiting	University of Giessen	2035-07-15
NCT04130243	Biomarkers in Pediatric Congenital Heart Disease and PAH	https://ClinicalTrials.gov/show/NCT04130243	Recruiting	University Medical Center Groningen	2021-12-01
NCT04071327	Pulmonary Hypertension Association Registry	https://ClinicalTrials.gov/show/NCT04071327	Recruiting	Pulmonary Hypertension Association, Inc.	2025-10-31
NCT04032379	Diagnostic and Prognostic Biomarkers of Idiopathic Intracranial Hypertension	https://ClinicalTrials.gov/show/NCT04032379	Recruiting	Danish Headache Center	2022-05-31
NCT04013503	National Tunisian Registry of Hypertension	https://ClinicalTrials.gov/show/NCT04013503	Completed	Dacima Consulting	2019-05-15
NCT04019600	Screening of Pulmonary Hypertension in Methamphetamine Abusers	https://ClinicalTrials.gov/show/NCT04019600	Recruiting	The University of Hong Kong	2022-12-22
NCT03959748	DataBase of pulmoNary hyPertesion in PoLish Population - BNP-PL	https://ClinicalTrials.gov/show/NCT03959748	Recruiting	Polish Cardiology Association	2023-02-28
NCT03954405	Multi-marker Approach for Risk Assessment in PAH	https://ClinicalTrials.gov/show/NCT03954405	Recruiting	Wuhan Asia Heart Hospital	2019-12-30
NCT03943420	One Research on Improving Cognitive Impairment Caused by Hypertension	https://ClinicalTrials.gov/show/NCT03943420	Recruiting	Jiangsu Famous Medical Technology Co., Ltd.	2020-12-31
NCT03933579	The PAH Platform for Deep Phenotyping in Korean Subjects	https://ClinicalTrials.gov/show/NCT03933579	Recruiting	Gachon University Gil Medical Center	2020-12-31
NCT03868384	The Effect of Home Blood Pressure Measurement on the Management of Hypertension	https://ClinicalTrials.gov/show/NCT03868384	Recruiting	DongGuk University	2025-12-31
NCT03781401	Telemonitoring of Blood Pressure in Local Pharmacies	https://ClinicalTrials.gov/show/NCT03781401	Recruiting	Italian Institute of Telemedicine	2018-12-31
NCT03719703	Health in Childhood Following Assisted Reproductive Technology	https://ClinicalTrials.gov/show/NCT03719703	Recruiting	Rigshospitalet, Denmark	2021-11-30
NCT03718585	Whole Exome Sequencing in CKD Hypertension	https://ClinicalTrials.gov/show/NCT03718585	Recruiting	Fifth Affiliated Hospital, Sun Yat-Sen University	2021-10-31
NCT03707561	RUS-registry of PH	https://ClinicalTrials.gov/show/NCT03707561	Enrolling by invitation	Russian Cardiology Research and Production Center	2020-12-31
NCT03688698	PET/MRI in PAH Patients	https://ClinicalTrials.gov/show/NCT03688698	Completed	Medical University of Bialystok	2017-06-01
NCT03667391	Taiwan Cohort - Chronic ThromboEmbolic Pulmonary Hypertension Registry	https://ClinicalTrials.gov/show/NCT03667391	Recruiting	National Taiwan University Hospital	2022-01-01
NCT03655288	A Post-marketing Surveillance to Assess Safety and Efficacy of Twotopsplus.	https://ClinicalTrials.gov/show/NCT03655288	Recruiting	IlDong Pharmaceutical Co Ltd	2023-05-31
NCT03559608	Arterial Hypertension in Men in the Warmia and Masuria Region	https://ClinicalTrials.gov/show/NCT03559608	Active, not recruiting	University of Warmia and Mazury	2017-12-23
NCT03513926	Molecular Profile of Cardiovascular Risk in Obstructive Sleep Apnea Patients: Personalized Predictive Model.	https://ClinicalTrials.gov/show/NCT03513926	Completed	Sociedad EspaÃ±ola de NeumologÃa y CirugÃa TorÃ¡cica	2018-01-31
NCT03484312	Hypertensive Urgency Treatment and Outcomes in a Northeast Thai Population	https://ClinicalTrials.gov/show/NCT03484312	Completed	Khon Kaen University	2017-06-30
NCT03932422	Central Hemodynamic and Sodium Urinary	https://ClinicalTrials.gov/show/NCT03932422	Active, not recruiting	Hospital de Base	2019-11-15
NCT01913457	Measurements and Characterization of Doppler Signals From the Right Chest in Pediatric and Adult Patients	https://ClinicalTrials.gov/show/NCT01913457	Recruiting	Echosense Ltd.	2020-03-31
NCT01834118	Reintervention-study After Previous Renal Denervation in Non-responding Patients With Severe Hypertension	https://ClinicalTrials.gov/show/NCT01834118	Completed	Cardiovascular Center Frankfurt	2016-04-30
NCT04289701	Hypertension Registry of “Hypertension Prevention and Control Initiative in China”	https://ClinicalTrials.gov/show/NCT04289701	Recruiting	Chinese Academy of Medical Sciences, Fuwai Hospital	2022-12-30
NCT03172429	Cerebral Tissue Oxygenation in Highlanders/Lowlanders	https://ClinicalTrials.gov/show/NCT03172429	Completed	University of Zurich	2017-08-16
NCT03169010	Registration Study for Rare Type of Pulmonary Hypertension	https://ClinicalTrials.gov/show/NCT03169010	Recruiting	China National Center for Cardiovascular Diseases	2022-12-31
NCT03165032	Right Ventricular Function During Exercise in Highlanders/Lowlanders	https://ClinicalTrials.gov/show/NCT03165032	Completed	University of Zurich	2017-08-16
NCT03165019	Time Course and Prognostic Significance of Pulmonary Artery Pressure in Highlanders.	https://ClinicalTrials.gov/show/NCT03165019	Completed	University of Zurich	2017-08-16

intervention_type	Study_Count
Drug	1258
Drug\|placebo	427
Behavioral	313
Other	249
Device	169
Procedure	81
Dietary Supplement	66
Dietary Supplement\|placebo	48
Drug\|Other	33
Drug\|Procedure	27
Behavioral\|Other	25
Device\|Other	23
Device\|Drug	16
Diagnostic Test	16
Behavioral\|Drug	15
Behavioral\|Device	11
Device\|Procedure	10
Other\|placebo	8
Other\|Procedure	8
Drug\|Other\|placebo	6
Biological	5
Dietary Supplement\|Drug\|placebo	5
placebo	5
Radiation	5
Combination Product	4
Device\|Drug\|placebo	4
Device\|Drug\|Procedure	4
Biological\|placebo	3
Device\|Diagnostic Test	3
Device\|placebo	3
Dietary Supplement\|Other	3
Behavioral\|Procedure	2
Combination Product\|placebo	2
Dietary Supplement\|Drug	2
Behavioral\|Device\|Other	1
Behavioral\|Dietary Supplement	1
Behavioral\|Dietary Supplement\|Other	1
Behavioral\|Dietary Supplement\|placebo	1
Behavioral\|Drug\|placebo	1
Biological\|Diagnostic Test\|Drug\|placebo	1
Biological\|Diagnostic Test\|Other	1
Biological\|Drug	1
Biological\|Drug\|placebo	1
Biological\|Other	1
Dietary Supplement\|Drug\|Other	1
Dietary Supplement\|Drug\|Other\|placebo	1
Dietary Supplement\|Procedure	1
Drug\|Other\|placebo\|Procedure	1
Drug\|placebo\|Procedure	1
Drug\|Radiation	1
Genetic	1
Other\|Procedure\|Radiation	1

hypertension

Study Counts

Studies over Time by Start Date

Interventional Trials

Intervention Type

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Studies by Country

Sites per Study

Phase

Number of Arms

Enrollment Metrics by Phase

Trial Group Type

Intervention Model

Primary Purpose

Observational Studies

Studies by Country

Sites per Study

Enrollment Metrics

Observation Model

Time Perspective

Registries

Studies by Country

Sites per Study

Enrollment Metrics

Registry Model

Time Perspective

Follow-up

Overview of Studies

Interventional Trials

Observational Studiess

Registries